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What is start up updsmf pcr 80010/26/2023 ![]() ![]() Although effective and accurate, the high throughput of this method was severely limited by reaction time and length of read, which is less than 1 kilobase, limiting use for single-gene testing or small-gene panels. Initially, the standard method of DNA sequencing technology most commonly in use was called Sanger sequencing. The identification of disease genes and their mutations hinges on the capability to sequence DNA to assess for detrimental alterations. Joseph Jankovic MD, in Bradley and Daroff's Neurology in Clinical Practice, 2022 Genome/Exome Sequencing in Clinical Practice, Disease Gene Discovery, and Gene Therapy
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